నైరూప్య

A case of neonatal lupus erythematosus presenting as hypopigmented atrophic scars

Hartati Purbo Dharmadji, Dhaifina Alkatirie, Oki Suwarsa, Endang Sutedja, Miranti Pangastuti & Hendra Gunawan

Background: Neonatal Lupus Erythematosus (NLE) is a variant of lupus erythematosus that affects neonates. Cutaneous manifestation is one of the most common clinical manifestations in NLE, including erythematous macules and patches. Hypopigmented atrophic scar is a rare cutaneous manifestation of NLE. Case Report: A case of NLE in a 19-day-old female infant, who was born from asymptomatic first gravida mother was reported. Physical examination showed hypopigmented atrophic scars on the scalp, face, neck, chest, and back. Results of Antinuclear Antibody (ANA) panel from this patient revealed +++ for anti-Ro/SSA, anti-La/SSB, and anti-Ro-S2 recombinant antigens, whereas ANA test from her mother was reactive with a speckled pattern. These findings supported the diagnosis of NLE. Conclusion: Several cutaneous manifestations can present in NLE with hypopigmented atrophic scars as rare presentation. The diagnosis of NLE is an important marker for the asymptomatic mothers, who have a tendency to develop autoimmune diseases.